EHD1-dependent traffic of IGF-1 receptor to the cell surface is essential for Ewing sarcoma tumorigenesis and metastasis

Overexpression of the EPS15 Homology Domain containing 1 (EHD1) protein has been linked to tumorigenesis but whether its core function as a regulator of intracellular traffic of cell surface receptors plays a role in oncogenesis remains unknown. We establish that EHD1 is overexpressed in Ewing sarco...

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Detalles Bibliográficos
Autores principales: Chakraborty, Sukanya, Bhat, Aaqib M., Mushtaq, Insha, Luan, Haitao, Kalluchi, Achyuth, Mirza, Sameer, Storck, Matthew D., Chaturvedi, Nagendra, Lopez-Guerrero, Jose Antonio, Llombart-Bosch, Antonio, Machado, Isidro, Scotlandi, Katia, Meza, Jane L., Ghosal, Gargi, Coulter, Donald W., Jordan Rowley, M., Band, Vimla, Mohapatra, Bhopal C., Band, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359273/
https://www.ncbi.nlm.nih.gov/pubmed/37474760
http://dx.doi.org/10.1038/s42003-023-05125-1

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