The copy number and mutational landscape of recurrent ovarian high-grade serous carcinoma

The drivers of recurrence and resistance in ovarian high grade serous carcinoma remain unclear. We investigate the acquisition of resistance by collecting tumour biopsies from a cohort of 276 women with relapsed ovarian high grade serous carcinoma in the BriTROC-1 study. Panel sequencing shows close...

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Detalles Bibliográficos
Autores principales: Smith, Philip, Bradley, Thomas, Gavarró, Lena Morrill, Goranova, Teodora, Ennis, Darren P., Mirza, Hasan B., De Silva, Dilrini, Piskorz, Anna M., Sauer, Carolin M., Al-Khalidi, Sarwah, Funingana, Ionut-Gabriel, Reinius, Marika A. V., Giannone, Gaia, Lewsley, Liz-Anne, Stobo, Jamie, McQueen, John, Bryson, Gareth, Eldridge, Matthew, Macintyre, Geoff, Markowetz, Florian, Brenton, James D., McNeish, Iain A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359414/
https://www.ncbi.nlm.nih.gov/pubmed/37474499
http://dx.doi.org/10.1038/s41467-023-39867-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359414/
https://www.ncbi.nlm.nih.gov/pubmed/37474499
http://dx.doi.org/10.1038/s41467-023-39867-7

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