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Regulation of T7 gp2.5 binding dynamics by its C-terminal tail, template conformation and sequence
Bacteriophage T7 single-stranded DNA-binding protein (gp2.5) binds to and protects transiently exposed regions of single-stranded DNA (ssDNA) while dynamically interacting with other proteins of the replication complex. We directly visualize fluorescently labelled T7 gp2.5 binding to ssDNA at the si...
Autores principales: | Xu, Longfu, Cabanas-Danés, Jordi, Halma, Matthew T J, Heller, Iddo, Stratmann, Sarah A, van Oijen, Antoine M, Lee, Seung-Joo, Peterman, Erwin J G, Wuite, Gijs J L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359462/ https://www.ncbi.nlm.nih.gov/pubmed/37254785 http://dx.doi.org/10.1093/nar/gkad485 |
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