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Dual chemical labeling enables nucleotide-resolution mapping of DNA abasic sites and common alkylation damage in human mitochondrial DNA

Mitochondrial DNA (mtDNA) modifications play an emerging role in innate immunity and inflammatory diseases. Nonetheless, relatively little is known regarding the locations of mtDNA modifications. Such information is critically important for deciphering their roles in mtDNA instability, mtDNA-mediate...

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Detalles Bibliográficos
Autores principales:	Liu, Chaoxing, Le, Brandon H, Xu, Wenyan, Yang, Ching-Hsin, Chen, Yu Hsuan, Zhao, Linlin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359467/ https://www.ncbi.nlm.nih.gov/pubmed/37293974 http://dx.doi.org/10.1093/nar/gkad502

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