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SIRT1 regulates DNA damage signaling through the PP4 phosphatase complex
The Sirtuin family of NAD(+)-dependent enzymes plays an important role in maintaining genome stability upon stress. Several mammalian Sirtuins have been linked directly or indirectly to the regulation of DNA damage during replication through Homologous recombination (HR). The role of one of them, SI...
Autores principales: | Rasti, George, Becker, Maximilian, Vazquez, Berta N, Espinosa-Alcantud, Maria, Fernández-Duran, Irene, Gámez-García, Andrés, Ianni, Alessandro, Gonzalez, Jessica, Bosch-Presegué, Laia, Marazuela-Duque, Anna, Guitart-Solanes, Anna, Segura-Bayona, Sandra, Bech-Serra, Joan-Josep, Scher, Michael, Serrano, Lourdes, Shankavaram, Uma, Erdjument-Bromage, Hediye, Tempst, Paul, Reinberg, Danny, Olivella, Mireia, Stracker, Travis H, de la Torre, Carolina, Vaquero, Alejandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359614/ https://www.ncbi.nlm.nih.gov/pubmed/37309898 http://dx.doi.org/10.1093/nar/gkad504 |
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