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Diagnostic value of Kaiser score combined with breast vascular assessment from breast MRI for the characterization of breast lesions
OBJECTIVES: The Kaiser scoring system for breast magnetic resonance imaging is a clinical decision-making tool for diagnosing breast lesions. However, the Kaiser score (KS) did not include the evaluation of breast vascularity. Therefore, this study aimed to use KS combined with breast vascular asses...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359820/ https://www.ncbi.nlm.nih.gov/pubmed/37483510 http://dx.doi.org/10.3389/fonc.2023.1165405 |
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author | Zhou, Xin-zhu Liu, Lian-hua He, Shuang Yao, Hui-fang Chen, Li-ping Deng, Chen Li, Shuang-Ling Zhang, Xiao-yong Lai, Hua |
author_facet | Zhou, Xin-zhu Liu, Lian-hua He, Shuang Yao, Hui-fang Chen, Li-ping Deng, Chen Li, Shuang-Ling Zhang, Xiao-yong Lai, Hua |
author_sort | Zhou, Xin-zhu |
collection | PubMed |
description | OBJECTIVES: The Kaiser scoring system for breast magnetic resonance imaging is a clinical decision-making tool for diagnosing breast lesions. However, the Kaiser score (KS) did not include the evaluation of breast vascularity. Therefore, this study aimed to use KS combined with breast vascular assessment, defined as KS(*), and investigate the effectiveness of KS(*) in differentiating benign from malignant breast lesions. METHODS: This retrospective study included 223 patients with suspicious breast lesions and pathologically verified results. The histopathological diagnostic criteria were according to the fifth edition of the WHO classification of breast tumors. The KS(*) was obtained after a joint evaluation combining the original KS and breast vasculature assessment. The receiver operating characteristic (ROC) curve was used for comparing differences in the diagnostic performance between KS(*) and KS, and the area under the receiver operating characteristic (AUC) was compared. RESULTS: There were 119 (53.4%) benign and 104 (46.6%) malignant lesions in total. The overall sensitivity, specificity, and accuracy of increased ipsilateral breast vascularity were 69.2%, 76.5%, and 73.1%, respectively. The overall sensitivity, specificity, and accuracy of AVS were 82.7%, 76.5%, and 79.4%, respectively. For all lesions included the AUC of KS(*) was greater than that of KS (0.877 vs. 0.858, P = 0.016). The largest difference in AUC was observed in the non-mass subgroup (0.793 vs. 0.725, P = 0.029). CONCLUSION: Ipsilaterally increased breast vascularity and a positive AVS sign were significantly associated with malignancy. KS combined with breast vascular assessment can effectively improve the diagnostic ability of KS for breast lesions, especially for non-mass lesions. |
format | Online Article Text |
id | pubmed-10359820 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-103598202023-07-22 Diagnostic value of Kaiser score combined with breast vascular assessment from breast MRI for the characterization of breast lesions Zhou, Xin-zhu Liu, Lian-hua He, Shuang Yao, Hui-fang Chen, Li-ping Deng, Chen Li, Shuang-Ling Zhang, Xiao-yong Lai, Hua Front Oncol Oncology OBJECTIVES: The Kaiser scoring system for breast magnetic resonance imaging is a clinical decision-making tool for diagnosing breast lesions. However, the Kaiser score (KS) did not include the evaluation of breast vascularity. Therefore, this study aimed to use KS combined with breast vascular assessment, defined as KS(*), and investigate the effectiveness of KS(*) in differentiating benign from malignant breast lesions. METHODS: This retrospective study included 223 patients with suspicious breast lesions and pathologically verified results. The histopathological diagnostic criteria were according to the fifth edition of the WHO classification of breast tumors. The KS(*) was obtained after a joint evaluation combining the original KS and breast vasculature assessment. The receiver operating characteristic (ROC) curve was used for comparing differences in the diagnostic performance between KS(*) and KS, and the area under the receiver operating characteristic (AUC) was compared. RESULTS: There were 119 (53.4%) benign and 104 (46.6%) malignant lesions in total. The overall sensitivity, specificity, and accuracy of increased ipsilateral breast vascularity were 69.2%, 76.5%, and 73.1%, respectively. The overall sensitivity, specificity, and accuracy of AVS were 82.7%, 76.5%, and 79.4%, respectively. For all lesions included the AUC of KS(*) was greater than that of KS (0.877 vs. 0.858, P = 0.016). The largest difference in AUC was observed in the non-mass subgroup (0.793 vs. 0.725, P = 0.029). CONCLUSION: Ipsilaterally increased breast vascularity and a positive AVS sign were significantly associated with malignancy. KS combined with breast vascular assessment can effectively improve the diagnostic ability of KS for breast lesions, especially for non-mass lesions. Frontiers Media S.A. 2023-07-06 /pmc/articles/PMC10359820/ /pubmed/37483510 http://dx.doi.org/10.3389/fonc.2023.1165405 Text en Copyright © 2023 Zhou, Liu, He, Yao, Chen, Deng, Li, Zhang and Lai https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology Zhou, Xin-zhu Liu, Lian-hua He, Shuang Yao, Hui-fang Chen, Li-ping Deng, Chen Li, Shuang-Ling Zhang, Xiao-yong Lai, Hua Diagnostic value of Kaiser score combined with breast vascular assessment from breast MRI for the characterization of breast lesions |
title | Diagnostic value of Kaiser score combined with breast vascular assessment from breast MRI for the characterization of breast lesions |
title_full | Diagnostic value of Kaiser score combined with breast vascular assessment from breast MRI for the characterization of breast lesions |
title_fullStr | Diagnostic value of Kaiser score combined with breast vascular assessment from breast MRI for the characterization of breast lesions |
title_full_unstemmed | Diagnostic value of Kaiser score combined with breast vascular assessment from breast MRI for the characterization of breast lesions |
title_short | Diagnostic value of Kaiser score combined with breast vascular assessment from breast MRI for the characterization of breast lesions |
title_sort | diagnostic value of kaiser score combined with breast vascular assessment from breast mri for the characterization of breast lesions |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359820/ https://www.ncbi.nlm.nih.gov/pubmed/37483510 http://dx.doi.org/10.3389/fonc.2023.1165405 |
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