Validation of metagenomic next-generation sequencing of bronchoalveolar lavage fluid for diagnosis of suspected pulmonary infections in patients with systemic autoimmune rheumatic diseases receiving immunosuppressant therapy

BACKGROUND: The accuracy and sensitivity of conventional microbiological tests (CMTs) are insufficient to identify opportunistic pathogens in patients with systemic autoimmune rheumatic diseases (SARDs). The study aimed to assess the usefulness of metagenomic next-generation sequencing (mNGS) vs. CM...

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Detalles Bibliográficos
Autores principales: Wen, Sichun, Peng, Siqi, Hu, Xuejiao, Jiang, Nan, Li, Bohou, Chen, Boxi, Deng, Shuting, Yuan, Ye, Wu, Qiong, Tao, Yiming, Ma, Jianchao, Li, Sijia, Lin, Ting, Wen, Feng, Li, Zhuo, Huang, Renwei, Feng, Zhonglin, He, Chaosheng, Wang, Wenjian, Liang, Xinling, Shi, Wei, Xu, Lixia, Liu, Shuangxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359889/
https://www.ncbi.nlm.nih.gov/pubmed/37484860
http://dx.doi.org/10.3389/fmed.2023.1161661

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