Chemical Evolution of Amphiphilic Xenopeptides for Potentiated Cas9 Ribonucleoprotein Delivery

[Image: see text] The introduction of the CRISPR/Cas9 system in the form of Cas9/sgRNA ribonucleoproteins (RNP) is an efficient, straightforward strategy for genome editing, and potent RNP carriers are in high demand. Here, we report a series of artificial peptides based on novel ionizable amino aci...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Yi, Luo, Xianjin, Burghardt, Tobias, Dorrer, Sarah, Höhn, Miriam, Wagner, Ernst, Lächelt, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360056/
https://www.ncbi.nlm.nih.gov/pubmed/37395536
http://dx.doi.org/10.1021/jacs.3c01902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360056/
https://www.ncbi.nlm.nih.gov/pubmed/37395536
http://dx.doi.org/10.1021/jacs.3c01902

Ejemplares similares