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Chemical Evolution of Amphiphilic Xenopeptides for Potentiated Cas9 Ribonucleoprotein Delivery

[Image: see text] The introduction of the CRISPR/Cas9 system in the form of Cas9/sgRNA ribonucleoproteins (RNP) is an efficient, straightforward strategy for genome editing, and potent RNP carriers are in high demand. Here, we report a series of artificial peptides based on novel ionizable amino aci...

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Detalles Bibliográficos
Autores principales:	Lin, Yi, Luo, Xianjin, Burghardt, Tobias, Dorrer, Sarah, Höhn, Miriam, Wagner, Ernst, Lächelt, Ulrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360056/ https://www.ncbi.nlm.nih.gov/pubmed/37395536 http://dx.doi.org/10.1021/jacs.3c01902

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