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Tunable Heteroaromatic Nitriles for Selective Bioorthogonal Click Reaction with Cysteine
[Image: see text] The binucleophilic properties of 1,2-aminothiol and its rare occurrence in nature make it a useful reporter for tracking molecules in living systems. The 1,2-aminothiol moiety is present in cysteine, which is a substrate for a biocompatible click reaction with heteroaromatic nitril...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360065/ https://www.ncbi.nlm.nih.gov/pubmed/37354098 http://dx.doi.org/10.1021/acs.bioconjchem.3c00163 |