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Tunable Heteroaromatic Nitriles for Selective Bioorthogonal Click Reaction with Cysteine

[Image: see text] The binucleophilic properties of 1,2-aminothiol and its rare occurrence in nature make it a useful reporter for tracking molecules in living systems. The 1,2-aminothiol moiety is present in cysteine, which is a substrate for a biocompatible click reaction with heteroaromatic nitril...

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Detalles Bibliográficos
Autores principales:	Proj, Matic, Strašek, Nika, Pajk, Stane, Knez, Damijan, Sosič, Izidor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360065/ https://www.ncbi.nlm.nih.gov/pubmed/37354098 http://dx.doi.org/10.1021/acs.bioconjchem.3c00163

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