Phosphorylated S6K1 and 4E-BP1 play different roles in constitutively active Rheb-mediated retinal ganglion cell survival and axon regeneration after optic nerve injury

Ras homolog enriched in brain (Rheb) is a small GTPase that activates mammalian target of rapamycin complex 1 (mTORC1). Previous studies have shown that constitutively active Rheb can enhance the regeneration of sensory axons after spinal cord injury by activating downstream effectors of mTOR. S6K1...

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Detalles Bibliográficos
Autores principales: Jiang, Jikuan, Zhang, Lusi, Zou, Jingling, Liu, Jingyuan, Yang, Jia, Jiang, Qian, Duan, Peiyun, Jiang, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360084/
https://www.ncbi.nlm.nih.gov/pubmed/37282486
http://dx.doi.org/10.4103/1673-5374.371372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360084/
https://www.ncbi.nlm.nih.gov/pubmed/37282486
http://dx.doi.org/10.4103/1673-5374.371372

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