Cargando…

Qualitative and Quantitative Secondary Metabolite Profiles in a Large Set of Sumatra Benzoin Samples

[Image: see text] Sumatra benzoin, a resin produced by Styrax benzoin and Styrax paralleloneurum, is used as an aromatic agent and may have the potential to be developed as a new agricultural fungicide. In this context, we performed a comprehensive metabolite profiling of a commercial grade A resin...

Descripción completa

Detalles Bibliográficos
Autores principales: Heng, Ming Yuan, Syafni, Nova, Ramseyer, Justine, Thuerig, Barbara, Tamm, Lucius, Hamburger, Matthias, Potterat, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360151/
https://www.ncbi.nlm.nih.gov/pubmed/37399340
http://dx.doi.org/10.1021/acs.jafc.3c01861
_version_ 1785076039614988288
author Heng, Ming Yuan
Syafni, Nova
Ramseyer, Justine
Thuerig, Barbara
Tamm, Lucius
Hamburger, Matthias
Potterat, Olivier
author_facet Heng, Ming Yuan
Syafni, Nova
Ramseyer, Justine
Thuerig, Barbara
Tamm, Lucius
Hamburger, Matthias
Potterat, Olivier
author_sort Heng, Ming Yuan
collection PubMed
description [Image: see text] Sumatra benzoin, a resin produced by Styrax benzoin and Styrax paralleloneurum, is used as an aromatic agent and may have the potential to be developed as a new agricultural fungicide. In this context, we performed a comprehensive metabolite profiling of a commercial grade A resin by high-performance liquid chromatography coupled with photodiode array detection, evaporative light scattering detection, and mass spectrometry (HPLC-PDA-ELSD-MS) analysis in combination with (1)H NMR. Thirteen compounds including a new cinnamic acid ester containing two p-coumaroyl residues were identified after preparative isolation. These compounds accounted for an estimated 90% of the crude resin according to (1)H NMR analysis. The two major constituents, p-coumaryl cinnamate (5) and sumaresinolic acid (11), were quantified by HPLC analysis. In a next step, the chemical profiles and the content in p-coumaryl cinnamate were compared in a large set of resin samples of different quality grades that were obtained from various commercial suppliers in Sumatra. The qualitative profiles of the samples were very similar, but significant quantitative differences were observed between different quality grades and origins of the samples for the relative contents.
format Online
Article
Text
id pubmed-10360151
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher American Chemical Society
record_format MEDLINE/PubMed
spelling pubmed-103601512023-07-22 Qualitative and Quantitative Secondary Metabolite Profiles in a Large Set of Sumatra Benzoin Samples Heng, Ming Yuan Syafni, Nova Ramseyer, Justine Thuerig, Barbara Tamm, Lucius Hamburger, Matthias Potterat, Olivier J Agric Food Chem [Image: see text] Sumatra benzoin, a resin produced by Styrax benzoin and Styrax paralleloneurum, is used as an aromatic agent and may have the potential to be developed as a new agricultural fungicide. In this context, we performed a comprehensive metabolite profiling of a commercial grade A resin by high-performance liquid chromatography coupled with photodiode array detection, evaporative light scattering detection, and mass spectrometry (HPLC-PDA-ELSD-MS) analysis in combination with (1)H NMR. Thirteen compounds including a new cinnamic acid ester containing two p-coumaroyl residues were identified after preparative isolation. These compounds accounted for an estimated 90% of the crude resin according to (1)H NMR analysis. The two major constituents, p-coumaryl cinnamate (5) and sumaresinolic acid (11), were quantified by HPLC analysis. In a next step, the chemical profiles and the content in p-coumaryl cinnamate were compared in a large set of resin samples of different quality grades that were obtained from various commercial suppliers in Sumatra. The qualitative profiles of the samples were very similar, but significant quantitative differences were observed between different quality grades and origins of the samples for the relative contents. American Chemical Society 2023-07-03 /pmc/articles/PMC10360151/ /pubmed/37399340 http://dx.doi.org/10.1021/acs.jafc.3c01861 Text en © 2023 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by/4.0/Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Heng, Ming Yuan
Syafni, Nova
Ramseyer, Justine
Thuerig, Barbara
Tamm, Lucius
Hamburger, Matthias
Potterat, Olivier
Qualitative and Quantitative Secondary Metabolite Profiles in a Large Set of Sumatra Benzoin Samples
title Qualitative and Quantitative Secondary Metabolite Profiles in a Large Set of Sumatra Benzoin Samples
title_full Qualitative and Quantitative Secondary Metabolite Profiles in a Large Set of Sumatra Benzoin Samples
title_fullStr Qualitative and Quantitative Secondary Metabolite Profiles in a Large Set of Sumatra Benzoin Samples
title_full_unstemmed Qualitative and Quantitative Secondary Metabolite Profiles in a Large Set of Sumatra Benzoin Samples
title_short Qualitative and Quantitative Secondary Metabolite Profiles in a Large Set of Sumatra Benzoin Samples
title_sort qualitative and quantitative secondary metabolite profiles in a large set of sumatra benzoin samples
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360151/
https://www.ncbi.nlm.nih.gov/pubmed/37399340
http://dx.doi.org/10.1021/acs.jafc.3c01861
work_keys_str_mv AT hengmingyuan qualitativeandquantitativesecondarymetaboliteprofilesinalargesetofsumatrabenzoinsamples
AT syafninova qualitativeandquantitativesecondarymetaboliteprofilesinalargesetofsumatrabenzoinsamples
AT ramseyerjustine qualitativeandquantitativesecondarymetaboliteprofilesinalargesetofsumatrabenzoinsamples
AT thuerigbarbara qualitativeandquantitativesecondarymetaboliteprofilesinalargesetofsumatrabenzoinsamples
AT tammlucius qualitativeandquantitativesecondarymetaboliteprofilesinalargesetofsumatrabenzoinsamples
AT hamburgermatthias qualitativeandquantitativesecondarymetaboliteprofilesinalargesetofsumatrabenzoinsamples
AT potteratolivier qualitativeandquantitativesecondarymetaboliteprofilesinalargesetofsumatrabenzoinsamples