Human Small Heat Shock Protein B8 Inhibits Protein Aggregation without Affecting the Native Folding Process

[Image: see text] Small Heat Shock Proteins (sHSPs) are key components of our Protein Quality Control system and are thought to act as reservoirs that neutralize irreversible protein aggregation. Yet, sHSPs can also act as sequestrases, promoting protein sequestration into aggregates, thus challengi...

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Detalles Bibliográficos
Autores principales: Choudhary, Dhawal, Mediani, Laura, Avellaneda, Mario J., Bjarnason, Sveinn, Alberti, Simon, Boczek, Edgar E., Heidarsson, Pétur O., Mossa, Alessandro, Carra, Serena, Tans, Sander J., Cecconi, Ciro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360156/
https://www.ncbi.nlm.nih.gov/pubmed/37411010
http://dx.doi.org/10.1021/jacs.3c02022

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