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Exploring the feasibility of using the ICER Evidence Rating Matrix for Comparative Clinical Effectiveness in assessing treatment benefit and certainty in the clinical evidence on orphan therapies for paediatric indications

BACKGROUND: The evaluation of clinical evidence takes account of health benefit (efficacy and safety) and the degree of certainty in the estimate of benefit. In orphan indications practical and ethical challenges in conducting clinical trials, particularly in paediatric patients, often limit the ava...

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Detalles Bibliográficos
Autores principales:	Wex, Jaro, Szkultecka-Debek, Monika, Drozd, Mariola, King, Sarah, Zibelnik, Natasa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360248/ https://www.ncbi.nlm.nih.gov/pubmed/37474954 http://dx.doi.org/10.1186/s13023-023-02701-w

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