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Bone-Derived IGF-I Regulates Radial Bone Growth in Adult Male Mice

Insulin-like growth factor-I (IGF-I) levels, which are reduced by age, and cortical bone dimensions are major determinants of fracture risk in elderly subjects. Inactivation of liver-derived circulating IGF-I results in reduced periosteal bone expansion in young and older mice. In mice with lifelong...

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Detalles Bibliográficos
Autores principales:	Svensson, Johan, Sjögren, Klara, Lawenius, Lina, Koskela, Antti, Tuukkanen, Juha, Nilsson, Karin H, Movérare-Skrtic, Sofia, Ohlsson, Claes
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360385/ https://www.ncbi.nlm.nih.gov/pubmed/37406213 http://dx.doi.org/10.1210/endocr/bqad104

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