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Development of a multiplex assay to assess activated p300/CBP in circulating prostate tumor cells

Reduced SIRT2 deacetylation and increased p300 acetylation activity leads to a concerted mechanism of hyperacetylation at specific histone lysine sites (H3K9, H3K14, and H3K18) in castration-resistant prostate cancer (CRPC). We examined whether circulating tumor cells (CTCs) identify patients with a...

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Detalles Bibliográficos
Autores principales:	Filon, Mikolaj, Yang, Bing, Purohit, Tanaya A., Schehr, Jennifer, Singh, Anupama, Bigarella, Marcelo, Lewis, Peter, Denu, John, Lang, Joshua, Jarrard, David F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360924/ https://www.ncbi.nlm.nih.gov/pubmed/37477521 http://dx.doi.org/10.18632/oncotarget.28477

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