Safety and efficacy of autologous skin tissue cells grafting for facial sunken or flat scars

IMPORTANCE: It is necessary to determine whether safety and efficacy of autologous skin tissue cells grafting for facial sunken or flat scars. OBJECTIVE: To identify autologous skin tissue cells grafting can reduce facial sunken or flat scars. DESIGN, SETTING, AND PARTICIPANTS: In this retrospective cross-sectional study, a total of 128 patients with scar (exclude pathological scar patients), who were receiving autologous skin tissue cells grafting therapy from January 1, 2016, to December 31, 2019. INTERVENTIONS: Autologous skin tissue cells grafting. MAIN OUTCOMES AND MEASURES: Changes in scar severity, color changes in the scar area, infection rate and patient satisfaction. RESULTS: A total of 128 patients with scar (89 females [69.5%]; mean [SD] age, 30.6 [13.12] years) received autologous skin tissue cells grafting therapy. SCAR (Scar Cosmesis Assessment and Rating), with scores ranging from 0 (best possible scar) to 15 (worst possible scar). After treatment 12 months, the mean [SD] of SCAR score went down from 9.85 [1.33] to 2.67 [1.21]. No infection was observed during treatment or recovery, and the main drawback after autologous skin tissue cells grafting is that the color recovery time is longer. The patient satisfaction 6 months after treatment was 85.2%, furthermore 12 months after treatment patient satisfaction was 94.7%. CONCLUSIONS AND RELEVANCE: In this study, autologous skin tissue cells grafting was safe and effective to treat facial scars. Therefore, autologous skin tissue cells grafting may be recommended as a reliable treatment for facial scar.