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Safety and efficacy of autologous skin tissue cells grafting for facial sunken or flat scars
IMPORTANCE: It is necessary to determine whether safety and efficacy of autologous skin tissue cells grafting for facial sunken or flat scars. OBJECTIVE: To identify autologous skin tissue cells grafting can reduce facial sunken or flat scars. DESIGN, SETTING, AND PARTICIPANTS: In this retrospective...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361016/ https://www.ncbi.nlm.nih.gov/pubmed/37484283 http://dx.doi.org/10.1016/j.heliyon.2023.e16992 |
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author | Liu, Tao Chen, Jinxi Wei, Bin Nie, Fangfang Zhu, Guanghui |
author_facet | Liu, Tao Chen, Jinxi Wei, Bin Nie, Fangfang Zhu, Guanghui |
author_sort | Liu, Tao |
collection | PubMed |
description | IMPORTANCE: It is necessary to determine whether safety and efficacy of autologous skin tissue cells grafting for facial sunken or flat scars. OBJECTIVE: To identify autologous skin tissue cells grafting can reduce facial sunken or flat scars. DESIGN, SETTING, AND PARTICIPANTS: In this retrospective cross-sectional study, a total of 128 patients with scar (exclude pathological scar patients), who were receiving autologous skin tissue cells grafting therapy from January 1, 2016, to December 31, 2019. INTERVENTIONS: Autologous skin tissue cells grafting. MAIN OUTCOMES AND MEASURES: Changes in scar severity, color changes in the scar area, infection rate and patient satisfaction. RESULTS: A total of 128 patients with scar (89 females [69.5%]; mean [SD] age, 30.6 [13.12] years) received autologous skin tissue cells grafting therapy. SCAR (Scar Cosmesis Assessment and Rating), with scores ranging from 0 (best possible scar) to 15 (worst possible scar). After treatment 12 months, the mean [SD] of SCAR score went down from 9.85 [1.33] to 2.67 [1.21]. No infection was observed during treatment or recovery, and the main drawback after autologous skin tissue cells grafting is that the color recovery time is longer. The patient satisfaction 6 months after treatment was 85.2%, furthermore 12 months after treatment patient satisfaction was 94.7%. CONCLUSIONS AND RELEVANCE: In this study, autologous skin tissue cells grafting was safe and effective to treat facial scars. Therefore, autologous skin tissue cells grafting may be recommended as a reliable treatment for facial scar. |
format | Online Article Text |
id | pubmed-10361016 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-103610162023-07-22 Safety and efficacy of autologous skin tissue cells grafting for facial sunken or flat scars Liu, Tao Chen, Jinxi Wei, Bin Nie, Fangfang Zhu, Guanghui Heliyon Research Article IMPORTANCE: It is necessary to determine whether safety and efficacy of autologous skin tissue cells grafting for facial sunken or flat scars. OBJECTIVE: To identify autologous skin tissue cells grafting can reduce facial sunken or flat scars. DESIGN, SETTING, AND PARTICIPANTS: In this retrospective cross-sectional study, a total of 128 patients with scar (exclude pathological scar patients), who were receiving autologous skin tissue cells grafting therapy from January 1, 2016, to December 31, 2019. INTERVENTIONS: Autologous skin tissue cells grafting. MAIN OUTCOMES AND MEASURES: Changes in scar severity, color changes in the scar area, infection rate and patient satisfaction. RESULTS: A total of 128 patients with scar (89 females [69.5%]; mean [SD] age, 30.6 [13.12] years) received autologous skin tissue cells grafting therapy. SCAR (Scar Cosmesis Assessment and Rating), with scores ranging from 0 (best possible scar) to 15 (worst possible scar). After treatment 12 months, the mean [SD] of SCAR score went down from 9.85 [1.33] to 2.67 [1.21]. No infection was observed during treatment or recovery, and the main drawback after autologous skin tissue cells grafting is that the color recovery time is longer. The patient satisfaction 6 months after treatment was 85.2%, furthermore 12 months after treatment patient satisfaction was 94.7%. CONCLUSIONS AND RELEVANCE: In this study, autologous skin tissue cells grafting was safe and effective to treat facial scars. Therefore, autologous skin tissue cells grafting may be recommended as a reliable treatment for facial scar. Elsevier 2023-06-07 /pmc/articles/PMC10361016/ /pubmed/37484283 http://dx.doi.org/10.1016/j.heliyon.2023.e16992 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Research Article Liu, Tao Chen, Jinxi Wei, Bin Nie, Fangfang Zhu, Guanghui Safety and efficacy of autologous skin tissue cells grafting for facial sunken or flat scars |
title | Safety and efficacy of autologous skin tissue cells grafting for facial sunken or flat scars |
title_full | Safety and efficacy of autologous skin tissue cells grafting for facial sunken or flat scars |
title_fullStr | Safety and efficacy of autologous skin tissue cells grafting for facial sunken or flat scars |
title_full_unstemmed | Safety and efficacy of autologous skin tissue cells grafting for facial sunken or flat scars |
title_short | Safety and efficacy of autologous skin tissue cells grafting for facial sunken or flat scars |
title_sort | safety and efficacy of autologous skin tissue cells grafting for facial sunken or flat scars |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361016/ https://www.ncbi.nlm.nih.gov/pubmed/37484283 http://dx.doi.org/10.1016/j.heliyon.2023.e16992 |
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