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Natural fulvic acids inhibit non-small-cell lung cancer through the COX-2/PGE2/EP4 axis: In silico and in vivo assessments

PURPOSE: Non-small-cell lung cancer (NSCLC) is a major public health concern with a high incidence worldwide. Coal-derived fulvic acids (FAs) contain functional groups in their chemical structures. Overexpression of cyclooxygenases-2 (COX-2), prostaglandin E2 (PGE2), and the PGE2 receptor EP4 subtyp...

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Detalles Bibliográficos
Autores principales:	Xin, Pengfei, Wang, Shirui, Xu, Xin, Liu, Qingmei, Zhang, Caifeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361232/ https://www.ncbi.nlm.nih.gov/pubmed/37484418 http://dx.doi.org/10.1016/j.heliyon.2023.e17080

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