Cargando…

Analysis of active components and molecular mechanism of action of Rubia cordifolia L. in the treatment of nasopharyngeal carcinoma based on network pharmacology and experimental verification

The aim of this study is to explore the active components and potential molecular mechanism of action of Rubia cordifolia L. against nasopharyngeal carcinoma (NPC). We used network pharmacology, molecular docking, and bioinformatics analysis to identify the active components and their role against N...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Ximing, Tao, Yangyang, Xu, Runshi, Luo, Wang, Lin, Ting, Zhou, Fangliang, Tang, Le, He, Lan, He, Yingchun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361237/ https://www.ncbi.nlm.nih.gov/pubmed/37484327 http://dx.doi.org/10.1016/j.heliyon.2023.e17078

Ejemplares similares

Analysis of the Molecular Mechanism of Evodia rutaecarpa Fruit in the Treatment of Nasopharyngeal Carcinoma Using Network Pharmacology and Molecular Docking
por: Xu, Runshi, et al.
Publicado: (2022)

COMPARATIVE STUDIES OF RUBIA CORDIFOLIA LINN. AND RUBIA TINCTORUM LINN (RUBIACEAE)(*)
por: Dengre, R.G., et al.
Publicado: (1993)

A comprehensive review of Rubia cordifolia L.: Traditional uses, phytochemistry, pharmacological activities, and clinical applications
por: Wen, Min, et al.
Publicado: (2022)

Anthraquinones from the Aerial Parts of Rubia cordifolia with Their NO Inhibitory and Antibacterial Activities
por: Luo, Han, et al.
Publicado: (2022)

The Underling Mechanisms Exploration of Rubia cordifolia L. Extract Against Rheumatoid Arthritis by Integrating Network Pharmacology and Metabolomics
por: Zeng, Weiya, et al.
Publicado: (2023)

Gastroprotective Effect of Rubia cordifolia Linn. on Aspirin Plus Pylorus-Ligated Ulcer
por: Deoda, R. S., et al.
Publicado: (2011)

In vitro Antiviral Activity of Rubia cordifolia Aerial Part Extract against Rotavirus
por: Sun, Yuanyuan, et al.
Publicado: (2016)

Rubiacordone A: A New Anthraquinone Glycoside from the Roots of Rubia cordifolia
por: Li, Xiang, et al.
Publicado: (2009)

Crosstalk of Cancer Signaling Pathways by Cyclic Hexapeptides and Anthraquinones from Rubia cordifolia
por: Balachandran, Premalatha, et al.
Publicado: (2021)

Protective Effect of Hydroalcoholic Root Extract of Rubia cordifolia in Indomethacin-Induced Enterocolitis in Rats
por: Pawar, A T, et al.
Publicado: (2011)

Anti-diarrheal and anti-inflammatory activities of aqueous extract of the aerial part of Rubia cordifolia
por: Gong, Xue-Peng, et al.
Publicado: (2017)

Rubia cordifolia L. Attenuates Diabetic Neuropathy by Inhibiting Apoptosis and Oxidative Stress in Rats
por: Bana, Sweeti, et al.
Publicado: (2023)

Molecular Assessment of Scutellaria barbata D. Don in the Treatment of Nasopharyngeal Carcinoma Based on Network Pharmacology and Experimental Verification
por: Shi, Hongjian, et al.
Publicado: (2022)

Therapeutic potential of biogenic and optimized silver nanoparticles using Rubia cordifolia L. leaf extract
por: Chandraker, Sandip Kumar, et al.
Publicado: (2022)

Rubia cordifolia, Fagonia cretica linn and Tinospora cordifolia exert neuroprotection by modulating the antioxidant system in rat hippocampal slices subjected to oxygen glucose deprivation
por: Rawal, Avinash K, et al.
Publicado: (2004)

Characterization of Rubia cordifolia L. root extract and its evaluation of cardioprotective effect in Wistar rat model
por: Chandrashekar, BS, et al.
Publicado: (2018)

The protective effect of Rubia cordifolia against lead nitrate-induced immune response impairment and kidney oxidative damage
por: lodi, Shweta, et al.
Publicado: (2011)

Phytochemical Characterization, Antioxidant and Anti-Proliferative Properties of Rubia cordifolia L. Extracts Prepared with Improved Extraction Conditions
por: Humbare, Ravikiran B., et al.
Publicado: (2022)

Chinese herbal extracts of Rubia cordifolia and Dianthus superbus suppress IgE production and prevent peanut-induced anaphylaxis
por: López-Expósito, Iván, et al.
Publicado: (2011)

Madder (Rubia cordifolia L.) Alleviates Myocardial Ischemia-Reperfusion Injury by Protecting Endothelial Cells from Apoptosis and Inflammation
por: Gao, Jinwei, et al.
Publicado: (2023)

Research Note: Effect of Rubia cordifolia L. processed Terminalia chebula Retz polysaccharide on the histological structure and apoptosis in the spleen in immunosuppressed Chinese yellow quail
por: He, Min, et al.
Publicado: (2022)

UPLC-QTOF-MS Identification of the Chemical Constituents in Rat Plasma and Urine after Oral Administration of Rubia cordifolia L. Extract
por: Zheng, Zuoliang, et al.
Publicado: (2017)

Rubias peligrosas
por: Echenoz, Jean
Publicado: (1998)

Dolicocéfala rubia /
por: Pitigrilli

Exploring the Effective Components and Mechanism of Action of Japanese Ardisia in the Treatment of Autoimmune Hepatitis Based on Network Pharmacology and Experimental Verification
por: Fu, Tian, et al.
Publicado: (2022)

TMARg, a Novel Anthraquinone Isolated from Rubia cordifolia Nakai, Increases Osteogenesis and Mineralization through BMP2 and β-Catenin Signaling
por: Park, Kyung-Ran, et al.
Publicado: (2020)

H(2)O-Induced Hydrophobic Interactions in MS-Guided Counter-Current Chromatography Separation of Anti-Cancer Mollugin from Rubia cordifolia
por: Zeng, Liping, et al.
Publicado: (2021)

Hyperthermia combined with immune checkpoint inhibitor therapy in the treatment of primary and metastatic tumors
por: Yang, Ximing, et al.
Publicado: (2022)

ZnO Nanoparticles of Rubia cordifolia Extract Formulation Developed and Optimized with QbD Application, Considering Ex Vivo Skin Permeation, Antimicrobial and Antioxidant Properties
por: Kaur, Jasmeet, et al.
Publicado: (2022)

A Review of the Botany, Phytochemistry, Pharmacology and Toxicology of Rubiae Radix et Rhizoma
por: Shan, Mingqiu, et al.
Publicado: (2016)

New Potential Pharmacological Targets of Plant-Derived Hydroxyanthraquinones from Rubia spp.
por: Alov, Petko, et al.
Publicado: (2022)

Three new triterpenoids from Rubia schumanniana
por: Kuang, Bin, et al.
Publicado: (2012)

Dr. Grenville on Rubia Tinctorum
por: Grenville, A. B.
Publicado: (1811)

The History of Madder (Rubia Tinctorum)
por: Cameron, G. R.
Publicado: (1932)

The chemical constituents and diverse pharmacological importance of Tinospora cordifolia
por: Sharma, Priyanka, et al.
Publicado: (2019)

Rubia cordifolia L. ameliorates DSS-induced ulcerative colitis in mice through dual inhibition of NLRP3 inflammasome and IL-6/JAK2/STAT3 pathways
por: Qin, Wei, et al.
Publicado: (2022)

Isoimperatorin Induces Apoptosis of Nasopharyngeal Carcinoma Cells via the MAPK/ERK1/2 Signaling Pathway
por: Liu, Jie, et al.
Publicado: (2020)

Effect of Tinospora cordifolia on experimental diabetic neuropathy
por: Nadig, Pratibha D., et al.
Publicado: (2012)

Therapeutic Application, Phytoactives and Pharmacology of Tinospora cordifolia: An Evocative Review
por: Ahsan, Rabiya, et al.
Publicado: (2023)

Luteolin Isolated from Polygonum cuspidatum Is a Potential Compound against Nasopharyngeal Carcinoma
por: Xiong, Yu, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0vkvqnnhtusef0tpmcvcb4mh3k