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Rational social distancing in epidemics with uncertain vaccination timing

During epidemics people may reduce their social and economic activity to lower their risk of infection. Such social distancing strategies will depend on information about the course of the epidemic but also on when they expect the epidemic to end, for instance due to vaccination. Typically it is dif...

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Detalles Bibliográficos
Autores principales: Schnyder, Simon K., Molina, John J., Yamamoto, Ryoichi, Turner, Matthew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361534/
https://www.ncbi.nlm.nih.gov/pubmed/37478107
http://dx.doi.org/10.1371/journal.pone.0288963
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author Schnyder, Simon K.
Molina, John J.
Yamamoto, Ryoichi
Turner, Matthew S.
author_facet Schnyder, Simon K.
Molina, John J.
Yamamoto, Ryoichi
Turner, Matthew S.
author_sort Schnyder, Simon K.
collection PubMed
description During epidemics people may reduce their social and economic activity to lower their risk of infection. Such social distancing strategies will depend on information about the course of the epidemic but also on when they expect the epidemic to end, for instance due to vaccination. Typically it is difficult to make optimal decisions, because the available information is incomplete and uncertain. Here, we show how optimal decision-making depends on information about vaccination timing in a differential game in which individual decision-making gives rise to Nash equilibria, and the arrival of the vaccine is described by a probability distribution. We predict stronger social distancing the earlier the vaccination is expected and also the more sharply peaked its probability distribution. In particular, equilibrium social distancing only meaningfully deviates from the no-vaccination equilibrium course if the vaccine is expected to arrive before the epidemic would have run its course. We demonstrate how the probability distribution of the vaccination time acts as a generalised form of discounting, with the special case of an exponential vaccination time distribution directly corresponding to regular exponential discounting.
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spelling pubmed-103615342023-07-22 Rational social distancing in epidemics with uncertain vaccination timing Schnyder, Simon K. Molina, John J. Yamamoto, Ryoichi Turner, Matthew S. PLoS One Research Article During epidemics people may reduce their social and economic activity to lower their risk of infection. Such social distancing strategies will depend on information about the course of the epidemic but also on when they expect the epidemic to end, for instance due to vaccination. Typically it is difficult to make optimal decisions, because the available information is incomplete and uncertain. Here, we show how optimal decision-making depends on information about vaccination timing in a differential game in which individual decision-making gives rise to Nash equilibria, and the arrival of the vaccine is described by a probability distribution. We predict stronger social distancing the earlier the vaccination is expected and also the more sharply peaked its probability distribution. In particular, equilibrium social distancing only meaningfully deviates from the no-vaccination equilibrium course if the vaccine is expected to arrive before the epidemic would have run its course. We demonstrate how the probability distribution of the vaccination time acts as a generalised form of discounting, with the special case of an exponential vaccination time distribution directly corresponding to regular exponential discounting. Public Library of Science 2023-07-21 /pmc/articles/PMC10361534/ /pubmed/37478107 http://dx.doi.org/10.1371/journal.pone.0288963 Text en © 2023 Schnyder et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Schnyder, Simon K.
Molina, John J.
Yamamoto, Ryoichi
Turner, Matthew S.
Rational social distancing in epidemics with uncertain vaccination timing
title Rational social distancing in epidemics with uncertain vaccination timing
title_full Rational social distancing in epidemics with uncertain vaccination timing
title_fullStr Rational social distancing in epidemics with uncertain vaccination timing
title_full_unstemmed Rational social distancing in epidemics with uncertain vaccination timing
title_short Rational social distancing in epidemics with uncertain vaccination timing
title_sort rational social distancing in epidemics with uncertain vaccination timing
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361534/
https://www.ncbi.nlm.nih.gov/pubmed/37478107
http://dx.doi.org/10.1371/journal.pone.0288963
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