Cargando…
Rational social distancing in epidemics with uncertain vaccination timing
During epidemics people may reduce their social and economic activity to lower their risk of infection. Such social distancing strategies will depend on information about the course of the epidemic but also on when they expect the epidemic to end, for instance due to vaccination. Typically it is dif...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361534/ https://www.ncbi.nlm.nih.gov/pubmed/37478107 http://dx.doi.org/10.1371/journal.pone.0288963 |
_version_ | 1785076238245691392 |
---|---|
author | Schnyder, Simon K. Molina, John J. Yamamoto, Ryoichi Turner, Matthew S. |
author_facet | Schnyder, Simon K. Molina, John J. Yamamoto, Ryoichi Turner, Matthew S. |
author_sort | Schnyder, Simon K. |
collection | PubMed |
description | During epidemics people may reduce their social and economic activity to lower their risk of infection. Such social distancing strategies will depend on information about the course of the epidemic but also on when they expect the epidemic to end, for instance due to vaccination. Typically it is difficult to make optimal decisions, because the available information is incomplete and uncertain. Here, we show how optimal decision-making depends on information about vaccination timing in a differential game in which individual decision-making gives rise to Nash equilibria, and the arrival of the vaccine is described by a probability distribution. We predict stronger social distancing the earlier the vaccination is expected and also the more sharply peaked its probability distribution. In particular, equilibrium social distancing only meaningfully deviates from the no-vaccination equilibrium course if the vaccine is expected to arrive before the epidemic would have run its course. We demonstrate how the probability distribution of the vaccination time acts as a generalised form of discounting, with the special case of an exponential vaccination time distribution directly corresponding to regular exponential discounting. |
format | Online Article Text |
id | pubmed-10361534 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-103615342023-07-22 Rational social distancing in epidemics with uncertain vaccination timing Schnyder, Simon K. Molina, John J. Yamamoto, Ryoichi Turner, Matthew S. PLoS One Research Article During epidemics people may reduce their social and economic activity to lower their risk of infection. Such social distancing strategies will depend on information about the course of the epidemic but also on when they expect the epidemic to end, for instance due to vaccination. Typically it is difficult to make optimal decisions, because the available information is incomplete and uncertain. Here, we show how optimal decision-making depends on information about vaccination timing in a differential game in which individual decision-making gives rise to Nash equilibria, and the arrival of the vaccine is described by a probability distribution. We predict stronger social distancing the earlier the vaccination is expected and also the more sharply peaked its probability distribution. In particular, equilibrium social distancing only meaningfully deviates from the no-vaccination equilibrium course if the vaccine is expected to arrive before the epidemic would have run its course. We demonstrate how the probability distribution of the vaccination time acts as a generalised form of discounting, with the special case of an exponential vaccination time distribution directly corresponding to regular exponential discounting. Public Library of Science 2023-07-21 /pmc/articles/PMC10361534/ /pubmed/37478107 http://dx.doi.org/10.1371/journal.pone.0288963 Text en © 2023 Schnyder et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Schnyder, Simon K. Molina, John J. Yamamoto, Ryoichi Turner, Matthew S. Rational social distancing in epidemics with uncertain vaccination timing |
title | Rational social distancing in epidemics with uncertain vaccination timing |
title_full | Rational social distancing in epidemics with uncertain vaccination timing |
title_fullStr | Rational social distancing in epidemics with uncertain vaccination timing |
title_full_unstemmed | Rational social distancing in epidemics with uncertain vaccination timing |
title_short | Rational social distancing in epidemics with uncertain vaccination timing |
title_sort | rational social distancing in epidemics with uncertain vaccination timing |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361534/ https://www.ncbi.nlm.nih.gov/pubmed/37478107 http://dx.doi.org/10.1371/journal.pone.0288963 |
work_keys_str_mv | AT schnydersimonk rationalsocialdistancinginepidemicswithuncertainvaccinationtiming AT molinajohnj rationalsocialdistancinginepidemicswithuncertainvaccinationtiming AT yamamotoryoichi rationalsocialdistancinginepidemicswithuncertainvaccinationtiming AT turnermatthews rationalsocialdistancinginepidemicswithuncertainvaccinationtiming |