Fatty acid desaturase 2 determines the lipidomic landscape and steroidogenic function of the adrenal gland

Corticosteroids regulate vital processes, including stress responses, systemic metabolism, and blood pressure. Here, we show that corticosteroid synthesis is related to the polyunsaturated fatty acid (PUFA) content of mitochondrial phospholipids in adrenocortical cells. Inhibition of the rate-limiti...

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Detalles Bibliográficos
Autores principales: Witt, Anke, Mateska, Ivona, Palladini, Alessandra, Sinha, Anupam, Wölk, Michele, Harauma, Akiko, Bechmann, Nicole, Pamporaki, Christina, Dahl, Andreas, Rothe, Michael, Kopaliani, Irakli, Adolf, Christian, Riester, Anna, Wielockx, Ben, Bornstein, Stefan R., Kroiss, Matthias, Peitzsch, Mirko, Moriguchi, Toru, Fedorova, Maria, Grzybek, Michal, Chavakis, Triantafyllos, Mirtschink, Peter, Alexaki, Vasileia Ismini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361602/
https://www.ncbi.nlm.nih.gov/pubmed/37478183
http://dx.doi.org/10.1126/sciadv.adf6710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361602/
https://www.ncbi.nlm.nih.gov/pubmed/37478183
http://dx.doi.org/10.1126/sciadv.adf6710

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