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The intricate mechanism of PLS3 in bone homeostasis and disease

Since our discovery in 2013 that genetic defects in PLS3 lead to bone fragility, the mechanistic details of this process have remained obscure. It has been established that PLS3 variants cause syndromic and nonsyndromic osteoporosis as well as osteoarthritis. PLS3 codes for an actin-bundling protein...

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Detalles Bibliográficos
Autores principales:	Zhong, Wenchao, Pathak, Janak L., Liang, Yueting, Zhytnik, Lidiia, Pals, Gerard, Eekhoff, Elisabeth M. W., Bravenboer, Nathalie, Micha, Dimitra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361617/ https://www.ncbi.nlm.nih.gov/pubmed/37484945 http://dx.doi.org/10.3389/fendo.2023.1168306

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