Structural modeling of antibody variable regions using deep learning—progress and perspectives on drug discovery

AlphaFold2 has hallmarked a generational improvement in protein structure prediction. In particular, advances in antibody structure prediction have provided a highly translatable impact on drug discovery. Though AlphaFold2 laid the groundwork for all proteins, antibody-specific applications require...

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Detalles Bibliográficos
Autores principales: Jaszczyszyn, Igor, Bielska, Weronika, Gawlowski, Tomasz, Dudzic, Pawel, Satława, Tadeusz, Kończak, Jarosław, Wilman, Wiktoria, Janusz, Bartosz, Wróbel, Sonia, Chomicz, Dawid, Galson, Jacob D., Leem, Jinwoo, Kelm, Sebastian, Krawczyk, Konrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361724/
https://www.ncbi.nlm.nih.gov/pubmed/37484529
http://dx.doi.org/10.3389/fmolb.2023.1214424

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