Regulatory B cells are reduced in the blood in patients with granulomatosis with polyangiitis, and fail to regulate T-cell IFN-γ production

Regulatory B (Breg) cells can dampen inflammation, autoreactivity, and transplant rejection. We investigated the frequencies, phenotypes, and function of Breg cells in granulomatosis with polyangiitis (GPA) to gain further knowledge as to whether there are numerical alterations or limitations of the...

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Detalles Bibliográficos
Autores principales: Appelgren, Daniel, Puli, Srinivasulu, Hellmark, Thomas, Pochard, Pierre, Pers, Jacques-Olivier, Ernerudh, Jan, Eriksson, Per, Segelmark, Mårten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Review Series: Human B Cells (Series Editors: Jo Spencer, Mats Bemark, Thomas J. Tull)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361745/
https://www.ncbi.nlm.nih.gov/pubmed/36752779
http://dx.doi.org/10.1093/cei/uxad021

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