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B7-H3-targeted CAR T cell activity is enhanced by radiotherapy in solid cancers

Adoptive cell therapy utilizing T cells genetically modified to express a chimeric antigen receptor (CAR) has demonstrated promising clinical results in hematological malignancies. However, solid cancers have not seen a similar success due to multiple obstacles. Investigating these escape mechanisms...

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Detalles Bibliográficos
Autores principales:	Ventin, Marco, Cattaneo, Giulia, Maggs, Luke, Jia, Jingyu, Arya, Shahrzad, Ferrone, Soldano, Wang, Xinhui, Ferrone, Cristina R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361748/ https://www.ncbi.nlm.nih.gov/pubmed/37483496 http://dx.doi.org/10.3389/fonc.2023.1193963

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