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The prognostic and predictive role of tumor-infiltrating lymphocytes (FoxP3 + and CD8 +) and tumor-associated macrophages in early HER2 + breast cancer

PURPOSE: In HER2-positive (HER2 +) breast cancer, tumor-infiltrating lymphocytes (TILs) and tumor-associated macrophages (TAMs) may influence the efficacy of the HER2-antibody trastuzumab and the patient’s outcome. In this HER2 + patient cohort, our aim was to study the numbers of FoxP3 + regulatory...

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Detalles Bibliográficos
Autores principales: Jääskeläinen, Minna M., Tiainen, Satu, Siiskonen, Hanna, Ahtiainen, Maarit, Kuopio, Teijo, Rönkä, Aino, Kettunen, Tiia, Hämäläinen, Kirsi, Rilla, Kirsi, Harvima, Ilkka, Mannermaa, Arto, Auvinen, Päivi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361875/
https://www.ncbi.nlm.nih.gov/pubmed/37428418
http://dx.doi.org/10.1007/s10549-023-07017-8