Identification of a novel immune checkpoint molecule V-set immunoglobulin domain-containing 4 that leads to impaired immunity infiltration in pancreatic ductal adenocarcinoma

BACKGROUND: Checkpoint-based immunotherapy has failed to elicit responses in the majority of patients with pancreatic cancer. In our study, we aimed to identify the role of a novel immune checkpoint molecule V-set Ig domain-containing 4 (VSIG4) in pancreatic ductal adenocarcinoma (PDAC). METHODS: On...

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Detalles Bibliográficos
Autores principales: Jiang, Yongsheng, Han, Lijie, Yang, Jian, Yang, Minwei, Zhang, Jian, Xue, Meilin, Zhu, Youwei, Xiong, Cheng, Shi, Minmin, Zhao, Shiwei, Shen, Baiyong, Xu, Zhiwei, Jiang, Lingxi, Chen, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361881/
https://www.ncbi.nlm.nih.gov/pubmed/37097516
http://dx.doi.org/10.1007/s00262-023-03438-y

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