Engineering siRNA-loaded and RGDfC-targeted selenium nanoparticles for highly efficient silencing of DCBLD2 gene for colorectal cancer treatment

Effective and safe delivery of small interfering RNA (siRNA) by nanomaterials to cancer cells is one of the main challenges in cancer treatment. In this study, we constructed the selenium nanoparticles conjugated with RGDfC (one tumor-targeted polypeptide) to prepare a biocompatible gene vector (RGD...

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Detalles Bibliográficos
Autores principales: Huang, Hongli, Chen, Hanqing, Shou, Diwen, Quan, Ying, Cheng, Jiemin, Chen, Huiting, Ning, Gang, Li, Yongqiang, Xia, Yu, Zhou, Yongjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361954/
https://www.ncbi.nlm.nih.gov/pubmed/37477789
http://dx.doi.org/10.1186/s11671-023-03870-0

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