Diagnostic dilemma in a rare case of nonfunctional parathyroid carcinoma at a referral facility in Northern Tanzania

KEY CLINICAL MESSAGE: Rare cancer originating from parathyroid parenchymal cells. Preoperative diagnosis is often difficult. Presents with normal serum levels of calcium and parathyroid hormone. Treated by en bloc resection. Benefits of adjuvant therapy are unclear. ABSTRACT: Parathyroid carcinoma i...

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Autores principales: Mremi, Alex, Kayuza, Michael, Amsi, Patrick, Magwizi, Marco, Chussi, Desderius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362111/
https://www.ncbi.nlm.nih.gov/pubmed/37484743
http://dx.doi.org/10.1002/ccr3.7737
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author Mremi, Alex
Kayuza, Michael
Amsi, Patrick
Magwizi, Marco
Chussi, Desderius
author_facet Mremi, Alex
Kayuza, Michael
Amsi, Patrick
Magwizi, Marco
Chussi, Desderius
author_sort Mremi, Alex
collection PubMed
description KEY CLINICAL MESSAGE: Rare cancer originating from parathyroid parenchymal cells. Preoperative diagnosis is often difficult. Presents with normal serum levels of calcium and parathyroid hormone. Treated by en bloc resection. Benefits of adjuvant therapy are unclear. ABSTRACT: Parathyroid carcinoma is an uncommon endocrine tumor. Its typical presentation is that of primary hyperparathyroidism with elevated serum calcium and parathormone levels. Nonfunctioning carcinoma of the parathyroid gland with normal serum calcium levels is extremely rare. This paper describes a case of nonfunctioning parathyroid carcinoma and brief literature review thereof.
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spelling pubmed-103621112023-07-23 Diagnostic dilemma in a rare case of nonfunctional parathyroid carcinoma at a referral facility in Northern Tanzania Mremi, Alex Kayuza, Michael Amsi, Patrick Magwizi, Marco Chussi, Desderius Clin Case Rep Case Report KEY CLINICAL MESSAGE: Rare cancer originating from parathyroid parenchymal cells. Preoperative diagnosis is often difficult. Presents with normal serum levels of calcium and parathyroid hormone. Treated by en bloc resection. Benefits of adjuvant therapy are unclear. ABSTRACT: Parathyroid carcinoma is an uncommon endocrine tumor. Its typical presentation is that of primary hyperparathyroidism with elevated serum calcium and parathormone levels. Nonfunctioning carcinoma of the parathyroid gland with normal serum calcium levels is extremely rare. This paper describes a case of nonfunctioning parathyroid carcinoma and brief literature review thereof. John Wiley and Sons Inc. 2023-07-21 /pmc/articles/PMC10362111/ /pubmed/37484743 http://dx.doi.org/10.1002/ccr3.7737 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Report
Mremi, Alex
Kayuza, Michael
Amsi, Patrick
Magwizi, Marco
Chussi, Desderius
Diagnostic dilemma in a rare case of nonfunctional parathyroid carcinoma at a referral facility in Northern Tanzania
title Diagnostic dilemma in a rare case of nonfunctional parathyroid carcinoma at a referral facility in Northern Tanzania
title_full Diagnostic dilemma in a rare case of nonfunctional parathyroid carcinoma at a referral facility in Northern Tanzania
title_fullStr Diagnostic dilemma in a rare case of nonfunctional parathyroid carcinoma at a referral facility in Northern Tanzania
title_full_unstemmed Diagnostic dilemma in a rare case of nonfunctional parathyroid carcinoma at a referral facility in Northern Tanzania
title_short Diagnostic dilemma in a rare case of nonfunctional parathyroid carcinoma at a referral facility in Northern Tanzania
title_sort diagnostic dilemma in a rare case of nonfunctional parathyroid carcinoma at a referral facility in northern tanzania
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362111/
https://www.ncbi.nlm.nih.gov/pubmed/37484743
http://dx.doi.org/10.1002/ccr3.7737
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