Disruption of Golgi markers by two RILP-directed shRNAs in neurons: A new role for RILP or a neuron-specific off-target phenotype?

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In neurons, degradation of dendritic cargos requires RAB7 and dynein-mediated retrograde transport to somatic lysosomes. To test if the dynein adapter RAB-interacting lysosomal protein (RILP) mediated the recruitment of dynein to late endosomes for retrograde transport in dendrites, we obtained seve...

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Detalles Bibliográficos
Autores principales: Yap, Chan Choo, Digilio, Laura, McMahon, Lloyd, Winckler, Bettina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362152/
https://www.ncbi.nlm.nih.gov/pubmed/37315786
http://dx.doi.org/10.1016/j.jbc.2023.104916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362152/
https://www.ncbi.nlm.nih.gov/pubmed/37315786
http://dx.doi.org/10.1016/j.jbc.2023.104916

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