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Biological activities of 4H-thiochromen-4-one 1,1-dioxide derivatives against tropical disease parasites: A target-based drug design approach

A promising strategy for developing novel therapies against tropical diseases, including malaria, leishmaniasis, and trypanosomiasis, is to detect biological targets such as trypanothione reductase, a vital parasite enzyme that regulates oxidative stress. This enzyme is highly selective and conserve...

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Detalles Bibliográficos
Autores principales:	Ortiz, Cristian, Breuning, Matthias, Robledo, Sara, Echeverri, Fernando, Vargas, Esteban, Quiñones, Wiston
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362183/ https://www.ncbi.nlm.nih.gov/pubmed/37483711 http://dx.doi.org/10.1016/j.heliyon.2023.e17801

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