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Methionine oxidation selectively enhances T cell reactivity against a melanoma antigen

The impact of the peptide amino acids side-chain modifications on the immunological recognition has been scarcely explored. We investigate here the effect of methionine oxidation on the antigenicity of the melanoma immunodominant peptide 369-YMDGTMSQV-377 (YMD). Using CD8(+) T cell activation assays...

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Detalles Bibliográficos
Autores principales:	Chiriţoiu, Gabriela N., Munteanu, Cristian V.A., Şulea, Teodor A., Spiridon, Laurenţiu, Petrescu, Andrei-Jose, Jandus, Camilla, Romero, Pedro, Petrescu, Ştefana M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362274/ https://www.ncbi.nlm.nih.gov/pubmed/37485346 http://dx.doi.org/10.1016/j.isci.2023.107205

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