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Assessment of quality of commercial hand sanitizers using Fourier transform infrared spectroscopy and gas chromatography

Since the beginning of the COVID-19 pandemic, the use and manufacture of alcohol-based hand sanitizers increased exponentially. Efficacy of hand sanitizers mainly depends on active ingredients like ethanol and isopropanol (IPA). Even though methanol is extremely hazardous to people, it is still ille...

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Detalles Bibliográficos
Autores principales: Alam, Saima, Rahat, Md. Masudur Rahman, Upoma, Nusrat Jahan, Halder, Chandan, Moulick, Shyama Prosad, Islam, Md. Monarul, Liu, Wenben, Habib, Ahsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362314/
https://www.ncbi.nlm.nih.gov/pubmed/37484519
http://dx.doi.org/10.1016/j.mex.2023.102274
Descripción
Sumario:Since the beginning of the COVID-19 pandemic, the use and manufacture of alcohol-based hand sanitizers increased exponentially. Efficacy of hand sanitizers mainly depends on active ingredients like ethanol and isopropanol (IPA). Even though methanol is extremely hazardous to people, it is still illegally used in hand sanitizers in Bangladesh. Developing a quick and simple analytical method for detecting and quantifying ethanol/IPA/methanol is crucial. Here, Fourier transform infrared spectroscopy (FTIR) was used to identify and quantify alcohol content in commercially available hand sanitizers in a quick and easy way. Comparing the FTIR and GC data, provided quite similar results. Unlike previous studies by FTIR, C–H, CH(3)–C–CH(3) • FTIR was used to identify and quantify alcohol content in commercially available hand sanitizers in a quick and easy way. • Comparing the FTIR and GC data, provided quite similar results. • Out of ten samples, five contained ethanol, three IPA, and two methanol.