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PharmaChain: Blockchain-based drug supply chain provenance verification system

Over the last decade, pharmaceutical businesses have battled to standardize product traceability across the supply chain process, enabling counterfeiters to enter the market with counterfeit pharmaceuticals. As a result, an end-to-end product tracking system is crucial for ensuring product safety an...

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Detalles Bibliográficos
Autores principales: Gomasta, Sarmistha Sarna, Dhali, Aditi, Tahlil, Tahlil, Anwar, Md. Musfique, Ali, A.B. M Shawkat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362317/
https://www.ncbi.nlm.nih.gov/pubmed/37483827
http://dx.doi.org/10.1016/j.heliyon.2023.e17957
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author Gomasta, Sarmistha Sarna
Dhali, Aditi
Tahlil, Tahlil
Anwar, Md. Musfique
Ali, A.B. M Shawkat
author_facet Gomasta, Sarmistha Sarna
Dhali, Aditi
Tahlil, Tahlil
Anwar, Md. Musfique
Ali, A.B. M Shawkat
author_sort Gomasta, Sarmistha Sarna
collection PubMed
description Over the last decade, pharmaceutical businesses have battled to standardize product traceability across the supply chain process, enabling counterfeiters to enter the market with counterfeit pharmaceuticals. As a result, an end-to-end product tracking system is crucial for ensuring product safety and eliminating counterfeit products across the pharmaceutical supply chain. In this paper, we introduce PharmaChain, a decentralized hyperledger fabric framework that leverages confidentiality, accountability, and interoperability. This system enables on-chain and off-chain storage for secured, rapid transactions, along with smart contracts establishing data provenance. To demonstrate security, we have provided double signing through the elliptic curve digital signature algorithm, hash data encryption, and 33% node attack. The purpose of this suggested framework is to engage particular governance disciplines to assess its effectiveness in improving drug traceability across the pharmaceutical supply chain to preserve public health by preventing counterfeit pharmaceuticals.
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spelling pubmed-103623172023-07-23 PharmaChain: Blockchain-based drug supply chain provenance verification system Gomasta, Sarmistha Sarna Dhali, Aditi Tahlil, Tahlil Anwar, Md. Musfique Ali, A.B. M Shawkat Heliyon Research Article Over the last decade, pharmaceutical businesses have battled to standardize product traceability across the supply chain process, enabling counterfeiters to enter the market with counterfeit pharmaceuticals. As a result, an end-to-end product tracking system is crucial for ensuring product safety and eliminating counterfeit products across the pharmaceutical supply chain. In this paper, we introduce PharmaChain, a decentralized hyperledger fabric framework that leverages confidentiality, accountability, and interoperability. This system enables on-chain and off-chain storage for secured, rapid transactions, along with smart contracts establishing data provenance. To demonstrate security, we have provided double signing through the elliptic curve digital signature algorithm, hash data encryption, and 33% node attack. The purpose of this suggested framework is to engage particular governance disciplines to assess its effectiveness in improving drug traceability across the pharmaceutical supply chain to preserve public health by preventing counterfeit pharmaceuticals. Elsevier 2023-07-10 /pmc/articles/PMC10362317/ /pubmed/37483827 http://dx.doi.org/10.1016/j.heliyon.2023.e17957 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Article
Gomasta, Sarmistha Sarna
Dhali, Aditi
Tahlil, Tahlil
Anwar, Md. Musfique
Ali, A.B. M Shawkat
PharmaChain: Blockchain-based drug supply chain provenance verification system
title PharmaChain: Blockchain-based drug supply chain provenance verification system
title_full PharmaChain: Blockchain-based drug supply chain provenance verification system
title_fullStr PharmaChain: Blockchain-based drug supply chain provenance verification system
title_full_unstemmed PharmaChain: Blockchain-based drug supply chain provenance verification system
title_short PharmaChain: Blockchain-based drug supply chain provenance verification system
title_sort pharmachain: blockchain-based drug supply chain provenance verification system
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362317/
https://www.ncbi.nlm.nih.gov/pubmed/37483827
http://dx.doi.org/10.1016/j.heliyon.2023.e17957
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