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PharmaChain: Blockchain-based drug supply chain provenance verification system
Over the last decade, pharmaceutical businesses have battled to standardize product traceability across the supply chain process, enabling counterfeiters to enter the market with counterfeit pharmaceuticals. As a result, an end-to-end product tracking system is crucial for ensuring product safety an...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362317/ https://www.ncbi.nlm.nih.gov/pubmed/37483827 http://dx.doi.org/10.1016/j.heliyon.2023.e17957 |
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author | Gomasta, Sarmistha Sarna Dhali, Aditi Tahlil, Tahlil Anwar, Md. Musfique Ali, A.B. M Shawkat |
author_facet | Gomasta, Sarmistha Sarna Dhali, Aditi Tahlil, Tahlil Anwar, Md. Musfique Ali, A.B. M Shawkat |
author_sort | Gomasta, Sarmistha Sarna |
collection | PubMed |
description | Over the last decade, pharmaceutical businesses have battled to standardize product traceability across the supply chain process, enabling counterfeiters to enter the market with counterfeit pharmaceuticals. As a result, an end-to-end product tracking system is crucial for ensuring product safety and eliminating counterfeit products across the pharmaceutical supply chain. In this paper, we introduce PharmaChain, a decentralized hyperledger fabric framework that leverages confidentiality, accountability, and interoperability. This system enables on-chain and off-chain storage for secured, rapid transactions, along with smart contracts establishing data provenance. To demonstrate security, we have provided double signing through the elliptic curve digital signature algorithm, hash data encryption, and 33% node attack. The purpose of this suggested framework is to engage particular governance disciplines to assess its effectiveness in improving drug traceability across the pharmaceutical supply chain to preserve public health by preventing counterfeit pharmaceuticals. |
format | Online Article Text |
id | pubmed-10362317 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-103623172023-07-23 PharmaChain: Blockchain-based drug supply chain provenance verification system Gomasta, Sarmistha Sarna Dhali, Aditi Tahlil, Tahlil Anwar, Md. Musfique Ali, A.B. M Shawkat Heliyon Research Article Over the last decade, pharmaceutical businesses have battled to standardize product traceability across the supply chain process, enabling counterfeiters to enter the market with counterfeit pharmaceuticals. As a result, an end-to-end product tracking system is crucial for ensuring product safety and eliminating counterfeit products across the pharmaceutical supply chain. In this paper, we introduce PharmaChain, a decentralized hyperledger fabric framework that leverages confidentiality, accountability, and interoperability. This system enables on-chain and off-chain storage for secured, rapid transactions, along with smart contracts establishing data provenance. To demonstrate security, we have provided double signing through the elliptic curve digital signature algorithm, hash data encryption, and 33% node attack. The purpose of this suggested framework is to engage particular governance disciplines to assess its effectiveness in improving drug traceability across the pharmaceutical supply chain to preserve public health by preventing counterfeit pharmaceuticals. Elsevier 2023-07-10 /pmc/articles/PMC10362317/ /pubmed/37483827 http://dx.doi.org/10.1016/j.heliyon.2023.e17957 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Research Article Gomasta, Sarmistha Sarna Dhali, Aditi Tahlil, Tahlil Anwar, Md. Musfique Ali, A.B. M Shawkat PharmaChain: Blockchain-based drug supply chain provenance verification system |
title | PharmaChain: Blockchain-based drug supply chain provenance verification system |
title_full | PharmaChain: Blockchain-based drug supply chain provenance verification system |
title_fullStr | PharmaChain: Blockchain-based drug supply chain provenance verification system |
title_full_unstemmed | PharmaChain: Blockchain-based drug supply chain provenance verification system |
title_short | PharmaChain: Blockchain-based drug supply chain provenance verification system |
title_sort | pharmachain: blockchain-based drug supply chain provenance verification system |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362317/ https://www.ncbi.nlm.nih.gov/pubmed/37483827 http://dx.doi.org/10.1016/j.heliyon.2023.e17957 |
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