Identification and cross-species comparison of in vitro phase I brevetoxin (BTX-2) metabolites in northern Gulf of Mexico fish and human liver microsomes by UHPLC-HRMS(/MS)

Brevetoxins (BTX) are a group of marine neurotoxins produced by the harmful alga Karenia brevis. Numerous studies have shown that BTX are rapidly accumulated and metabolized in shellfish and mammals. However, there are only limited data on BTX metabolism in fish, despite growing evidence that fish s...

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Detalles Bibliográficos
Autores principales: Gwinn, Jessica Kay, Robertson, Alison, Ivanova, Lada, Fæste, Christiane Kruse, Kryuchkov, Fedor, Uhlig, Silvio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Environmental toxin
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362319/
https://www.ncbi.nlm.nih.gov/pubmed/37483846
http://dx.doi.org/10.1016/j.toxcx.2023.100168

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