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Selection of potential natural compounds for poly-ADP-ribose polymerase (PARP) inhibition in glioblastoma therapy by in silico screening methods

Glioblastoma (GBM), the most prevalent brain tumor, is one of the least treatable malignancies due to its propensity for intracranial spread, high proliferative potential, and innate resistance to radiation and chemotherapy. Current GBM therapy is limited due to unfavorable, non-specific therapeutic...

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Detalles Bibliográficos
Autores principales: Tharamelveliyil Rajendran, Arunraj, Dheeraj Rajesh, Gupta, Kumar, Pankaj, Shivam Raju Dwivedi, Prarambh, Shashidhara Shastry, Chakrakodi, Narayanan Vadakkepushpakath, Anoop
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362462/
https://www.ncbi.nlm.nih.gov/pubmed/37485452
http://dx.doi.org/10.1016/j.sjbs.2023.103698