Prevalence of Low-Frequency, Antiviral Resistance Variants in SARS-CoV-2 Isolates in Ontario, Canada, 2020-2023

IMPORTANCE: Nirmatrelvir-ritonavir is an oral antiviral medication that improves outcomes in SARS-CoV-2 infections. However, there is concern that antiviral resistance will develop and that these viruses could be selected for after treatment. OBJECTIVE: To determine the prevalence of low-frequency S...

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Detalles Bibliográficos
Autores principales: Sjaarda, Calvin P., Lau, Lynette, Simpson, Jared T., Fattouh, Ramzi, Biondi, Mia J., Maguire, Finlay, Campigotto, Aaron, Feng, Yujia, Tozer, Kyla, Wong, Henry, Sung, Wilson W. L., Kim, Sean, Marshall, Christian R., Sheth, Prameet M., Kozak, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2023
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362469/
https://www.ncbi.nlm.nih.gov/pubmed/37477915
http://dx.doi.org/10.1001/jamanetworkopen.2023.24963

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