USP1 promotes the aerobic glycolysis and progression of T-cell acute lymphoblastic leukemia via PLK1/LDHA axis

The effect of aerobic glycolysis remains elusive in pediatric T-cell acute lymphoblastic leukemia (T-ALL). Increasing evidence has revealed that dysregulation of deubiquitination is involved in glycolysis, by targeting glycolytic rate-limiting enzymes. Here, we demonstrated that upregulated deubiqui...

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Detalles Bibliográficos
Autores principales: Liu, Shuguang, Xiang, Yuening, Wang, Boshi, Gao, Chao, Chen, Zhenping, Xie, Shao, Wu, Jing, Liu, Yi, Zhao, Xiaoxi, Yang, Chao, Yue, Zhixia, Wang, Linya, Wen, Xiaojia, Zhang, Ruidong, Zhang, Feng, Xu, Heng, Zhai, Xiaowen, Zheng, Huyong, Zhang, Hui, Qian, Maoxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Lymphoid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362547/
https://www.ncbi.nlm.nih.gov/pubmed/36912760
http://dx.doi.org/10.1182/bloodadvances.2022008284

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