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Causal discovery approach with reinforcement learning for risk factors of type II diabetes mellitus

BACKGROUND: Statistical correlation analysis is currently the most typically used approach for investigating the risk factors of type 2 diabetes mellitus (T2DM). However, this approach does not readily reveal the causal relationships between risk factors and rarely describes the causal relationships...

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Autores principales: Gao, Xiu-E., Hu, Jian-Gang, Chen, Bo, Wang, Yun-Ming, zhou, Sheng-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362703/
https://www.ncbi.nlm.nih.gov/pubmed/37480046
http://dx.doi.org/10.1186/s12859-023-05405-x
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author Gao, Xiu-E.
Hu, Jian-Gang
Chen, Bo
Wang, Yun-Ming
zhou, Sheng-Bin
author_facet Gao, Xiu-E.
Hu, Jian-Gang
Chen, Bo
Wang, Yun-Ming
zhou, Sheng-Bin
author_sort Gao, Xiu-E.
collection PubMed
description BACKGROUND: Statistical correlation analysis is currently the most typically used approach for investigating the risk factors of type 2 diabetes mellitus (T2DM). However, this approach does not readily reveal the causal relationships between risk factors and rarely describes the causal relationships visually. RESULTS: Considering the superiority of reinforcement learning in prediction, a causal discovery approach with reinforcement learning for T2DM risk factors is proposed herein. First, a reinforcement learning model is constructed for T2DM risk factors. Second, the process involved in the causal discovery method for T2DM risk factors is detailed. Finally, several experiments are designed based on diabetes datasets and used to verify the proposed approach. CONCLUSIONS: The experimental results show that the proposed approach improves the accuracy of causality mining between T2DM risk factors and provides new evidence to researchers engaged in T2DM prevention and treatment research.
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spelling pubmed-103627032023-07-23 Causal discovery approach with reinforcement learning for risk factors of type II diabetes mellitus Gao, Xiu-E. Hu, Jian-Gang Chen, Bo Wang, Yun-Ming zhou, Sheng-Bin BMC Bioinformatics Research BACKGROUND: Statistical correlation analysis is currently the most typically used approach for investigating the risk factors of type 2 diabetes mellitus (T2DM). However, this approach does not readily reveal the causal relationships between risk factors and rarely describes the causal relationships visually. RESULTS: Considering the superiority of reinforcement learning in prediction, a causal discovery approach with reinforcement learning for T2DM risk factors is proposed herein. First, a reinforcement learning model is constructed for T2DM risk factors. Second, the process involved in the causal discovery method for T2DM risk factors is detailed. Finally, several experiments are designed based on diabetes datasets and used to verify the proposed approach. CONCLUSIONS: The experimental results show that the proposed approach improves the accuracy of causality mining between T2DM risk factors and provides new evidence to researchers engaged in T2DM prevention and treatment research. BioMed Central 2023-07-21 /pmc/articles/PMC10362703/ /pubmed/37480046 http://dx.doi.org/10.1186/s12859-023-05405-x Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Gao, Xiu-E.
Hu, Jian-Gang
Chen, Bo
Wang, Yun-Ming
zhou, Sheng-Bin
Causal discovery approach with reinforcement learning for risk factors of type II diabetes mellitus
title Causal discovery approach with reinforcement learning for risk factors of type II diabetes mellitus
title_full Causal discovery approach with reinforcement learning for risk factors of type II diabetes mellitus
title_fullStr Causal discovery approach with reinforcement learning for risk factors of type II diabetes mellitus
title_full_unstemmed Causal discovery approach with reinforcement learning for risk factors of type II diabetes mellitus
title_short Causal discovery approach with reinforcement learning for risk factors of type II diabetes mellitus
title_sort causal discovery approach with reinforcement learning for risk factors of type ii diabetes mellitus
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362703/
https://www.ncbi.nlm.nih.gov/pubmed/37480046
http://dx.doi.org/10.1186/s12859-023-05405-x
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