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KRAS activation in gastric cancer stem-like cells promotes tumor angiogenesis and metastasis

Our previous work showed that KRAS activation in gastric cancer cells leads to activation of an epithelial-to-mesenchymal transition (EMT) program and generation of cancer stem-like cells (CSCs). Here we analyze how this KRAS activation in gastric CSCs promotes tumor angiogenesis and metastasis. Gas...

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Detalles Bibliográficos
Autores principales: Yoon, Changhwan, Lu, Jun, Jun, Yukyung, Suh, Yun-Suhk, Kim, Bang-Jin, Till, Jacob E., Kim, Jong Hyun, Keshavjee, Sara H., Ryeom, Sandra, Yoon, Sam S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362758/
https://www.ncbi.nlm.nih.gov/pubmed/37481516
http://dx.doi.org/10.1186/s12885-023-11170-0

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