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Alzheimer’s disease-associated complement gene variants influence plasma complement protein levels

BACKGROUND: Alzheimer’s disease (AD) has been associated with immune dysregulation in biomarker and genome-wide association studies (GWAS). GWAS hits include the genes encoding complement regulators clusterin (CLU) and complement receptor 1 (CR1), recognised as key players in AD pathology, and compl...

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Detalles Bibliográficos
Autores principales:	Veteleanu, Aurora, Stevenson-Hoare, Joshua, Keat, Samuel, Daskoulidou, Nikoleta, Zetterberg, Henrik, Heslegrave, Amanda, Escott-Price, Valentina, Williams, Julie, Sims, Rebecca, Zelek, Wioleta M., Carpanini, Sarah M., Morgan, Bryan Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362776/ https://www.ncbi.nlm.nih.gov/pubmed/37480051 http://dx.doi.org/10.1186/s12974-023-02850-6

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