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Screening and molecular dynamics simulation of compounds inhibiting MurB enzyme of drug-resistant Mycobacterium tuberculosis: An in-silico approach

Mycobacterium tuberculosis (MTB) is becoming more and more resistant to drugs and it is a common problem, making current antimicrobials ineffective and highlighting the need for new TB drugs. One of the promising targets for treating MTB is MurB enzymes. This study aimed to identify potential inhibi...

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Detalles Bibliográficos
Autores principales: Verma, Ankit, Kumar, Vijay, Naik, Bindu, Masood Khan, Javed, Singh, Pallavi, Erik Joakim Saris, Per, Gupta, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362793/
https://www.ncbi.nlm.nih.gov/pubmed/37483837
http://dx.doi.org/10.1016/j.sjbs.2023.103730