Cargando…

Screening and molecular dynamics simulation of compounds inhibiting MurB enzyme of drug-resistant Mycobacterium tuberculosis: An in-silico approach

Mycobacterium tuberculosis (MTB) is becoming more and more resistant to drugs and it is a common problem, making current antimicrobials ineffective and highlighting the need for new TB drugs. One of the promising targets for treating MTB is MurB enzymes. This study aimed to identify potential inhibi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Verma, Ankit, Kumar, Vijay, Naik, Bindu, Masood Khan, Javed, Singh, Pallavi, Erik Joakim Saris, Per, Gupta, Sanjay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362793/ https://www.ncbi.nlm.nih.gov/pubmed/37483837 http://dx.doi.org/10.1016/j.sjbs.2023.103730

Ejemplares similares

Double deletion of murA and murB induced temperature sensitivity in Corynebacterium glutamicum
por: Shi, Tuo, et al.
Publicado: (2019)

Substrate Channel Flexibility in Pseudomonas aeruginosa MurB Accommodates Two Distinct Substrates
por: Chen, Ming Wei, et al.
Publicado: (2013)

Mode action prediction of catechin from Uncaria gambir Roxb. against UDP-N-acetylenolpyruvyl-glucosamine reductase (MurB enzyme) of Streptococcus mutans: In silico study
por: Dharsono, Hendra Dian Adhita, et al.
Publicado: (2022)

Antifungal metabolites, their novel sources, and targets to combat drug resistance
por: Choudhary, Megha, et al.
Publicado: (2022)

Subtractive proteomics approach to Unravel the druggable proteins of the emerging pathogen Waddlia chondrophila and drug repositioning on its MurB protein
por: Chowdhury, Umar Faruq, et al.
Publicado: (2021)

Insight into phytase-producing microorganisms for phytate solubilization and soil sustainability
por: Rizwanuddin, Sheikh, et al.
Publicado: (2023)

The influence of airtightness on contaminant spread in MURBs in cold climates
por: Mckeen, Philip, et al.
Publicado: (2021)

Pullulanase: unleashing the power of enzyme with a promising future in the food industry
por: Naik, Bindu, et al.
Publicado: (2023)

Finger Millet (Eleusine coracana) Plant–Endophyte Dynamics: Plant Growth, Nutrient Uptake, and Zinc Biofortification
por: Chaudhary, Renu, et al.
Publicado: (2023)

Phytochemical Compounds, Acute Toxicity, Anti-Inflammatory and Antioxidant Activities of Thymus leptobotrys Murb Essential Oil
por: Oubihi, Asmaa, et al.
Publicado: (2023)

Conférence: The Wall / "Le mur"
por: Irivuzumugabe, Erik, et al.
Publicado: (2018)

Potential of MurA Enzyme and GBAP in Fsr Quorum Sensing System as Antibacterial Drugs Target: In vitro and In silico Study of Antibacterial Compounds from Myrmecodia pendans
por: Apriyanti, Eti, et al.
Publicado: (2021)

Le mur
por: Sartre, Jean-Paul, 1905-1980
Publicado: (1939)

Draft Genome Sequence of Novel Streptomyces sp. Strain AJ-1, Isolated from a Leafcutter Ant in Uttarakhand, India
por: Choudhary, Megha, et al.
Publicado: (2023)

Structure based virtual screening to identify inhibitors against MurE Enzyme of Mycobacterium tuberculosis using AutoDock Vina
por: Singh, Shilpi, et al.
Publicado: (2014)

Tr. Ferri Mur.
Publicado: (1879)

Crystallographic Study of Peptidoglycan Biosynthesis Enzyme MurD: Domain Movement Revisited
por: Šink, Roman, et al.
Publicado: (2016)

Inhibition of MurA Enzyme from Escherichia coli by Flavonoids and Their Synthetic Analogues
por: Frlan, Rok, et al.
Publicado: (2023)

Le mur du temps /
por: Jünger, Ernst, 1895-1998
Publicado: (1963)

Architecture and genomic arrangement of the MurE–MurF bacterial cell wall biosynthesis complex
por: Shirakawa, Karina T., et al.
Publicado: (2023)

Enolpyruvate transferase MurAA(A149E), identified during adaptation of Enterococcus faecium to daptomycin, increases stability of MurAA–MurG interaction
por: Zhou, Yue, et al.
Publicado: (2023)

Characterisation of ATP-Dependent Mur Ligases Involved in the Biogenesis of Cell Wall Peptidoglycan in Mycobacterium tuberculosis
por: Munshi, Tulika, et al.
Publicado: (2013)

Development of a one-pot assay for screening and identification of Mur pathway inhibitors in Mycobacterium tuberculosis
por: Eniyan, Kandasamy, et al.
Publicado: (2016)

Potential Allylpyrocatechol Derivatives as Antibacterial Agent Against Oral Pathogen of S. sanguinis ATCC 10,556 and as Inhibitor of MurA Enzymes: in vitro and in silico Study
por: Kurnia, Dikdik, et al.
Publicado: (2020)

Recent developments on UDP-N-acetylmuramoyl-L-alanine-D-gutamate ligase (Mur D) enzyme for antimicrobial drug development: An emphasis on in-silico approaches
por: Gaur, Vinita, et al.
Publicado: (2022)

Phage display-derived inhibitor of the essential cell wall biosynthesis enzyme MurF
por: Paradis-Bleau, Catherine, et al.
Publicado: (2008)

Design and Synthesis of Novel N-Benzylidenesulfonohydrazide Inhibitors of MurC and MurD as Potential Antibacterial Agents
por: Frlan, Rok, et al.
Publicado: (2008)

Phenolic Content, Antioxidant Activity, Anti-Inflammatory Potential, and Acute Toxicity Study of Thymus leptobotrys Murb. Extracts
por: Oubihi, Asmaa, et al.
Publicado: (2020)

Natrum Mur. in Its Antidotal Sphere
por: Guernsey, Wm. Jefferson
Publicado: (1887)

Bio-Mechanism Inhibitory Prediction of β-Sitosterol from Kemangi (Ocimum basilicum L.) as an Inhibitor of MurA Enzyme of Oral Bacteria: In vitro and in silico Study
por: Evangelina, Ida Ayu, et al.
Publicado: (2021)

An antibacterial from Hypericum acmosepalum inhibits ATP-dependent MurE ligase from Mycobacterium tuberculosis
por: Osman, Khadijo, et al.
Publicado: (2012)

Tetrahydroisoquinolines affect the whole-cell phenotype of Mycobacterium tuberculosis by inhibiting the ATP-dependent MurE ligase
por: Guzman, Juan D., et al.
Publicado: (2015)

Identification of two functional xyloglucan galactosyltransferase homologs BrMUR3 and BoMUR3 in brassicaceous vegetables
por: Wang, Meng, et al.
Publicado: (2020)

An Alternative and Conserved Cell Wall Enzyme That Can Substitute for the Lipid II Synthase MurG
por: Zhang, L., et al.
Publicado: (2021)

Chemical Composition, Allelopathic, Antioxidant, and Anti-Inflammatory Activities of Sesquiterpenes Rich Essential Oil of Cleome amblyocarpa Barratte & Murb.
por: Abd-ElGawad, Ahmed M., et al.
Publicado: (2021)

The Binding Mode of Second-Generation Sulfonamide Inhibitors of MurD: Clues for Rational Design of Potent MurD Inhibitors
por: Simčič, Mihael, et al.
Publicado: (2012)

N-acetylmuramic acid recognition by MurK kinase from the MurNAc auxotrophic oral pathogen Tannerella forsythia
por: Stasiak, Aleksandra Cecylia, et al.
Publicado: (2023)

Docking-based virtual screening of known drugs against murE of Mycobacterium tuberculosis towards repurposing for TB
por: Brindha, Sridharan, et al.
Publicado: (2016)

Berkeley : Mur de verre au plomb
Publicado: (1976)

Intermittent Fever: Eupat. Perf. Natrum Mur.
por: Millspaugh, C. F.
Publicado: (1882)

Cannot write session to /tmp/vufind_sessions/sess_f7i31d9hon00sbpjouj85vmshv