Phosphorylation of USP20 on Ser334 by IRAK1 promotes IL-1β-evoked signaling in vascular smooth muscle cells and vascular inflammation

Reversible lysine-63 (K63) polyubiquitination regulates proinflammatory signaling in vascular smooth muscle cells (SMCs) and plays an integral role in atherosclerosis. Ubiquitin-specific peptidase 20 (USP20) reduces NFκB activation triggered by proinflammatory stimuli, and USP20 activity attenuates...

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Detalles Bibliográficos
Autores principales: Zhang, Lisheng, Wu, Jiao-Hui, Jean-Charles, Pierre-Yves, Murali, Pavitra, Zhang, Wenli, Jazic, Aeva, Kaur, Suneet, Nepliouev, Igor, Stiber, Jonathan A., Snow, Kamie, Freedman, Neil J., Shenoy, Sudha K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362797/
https://www.ncbi.nlm.nih.gov/pubmed/37311534
http://dx.doi.org/10.1016/j.jbc.2023.104911

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