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Current Evidence and Future Perspectives about the Role of PARP Inhibitors in the Treatment of Thoracic Cancers

In recent years, poly (ADP-ribose) polymerase (PARP) inhibition has become a promising therapeutic option for several tumors, especially for those harboring a BRCA 1–2 mutation or a deficit in the homologous recombination repair (HRR) pathway. Nevertheless, to date, PARP inhibitors are still not lar...

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Detalles Bibliográficos
Autores principales: Parisi, Alessandro, Rossi, Francesca, De Filippis, Chiara, Paoloni, Francesco, Felicetti, Cristiano, Mammarella, Alex, Pecci, Federica, Lupi, Alessio, Berardi, Rossana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362869/
https://www.ncbi.nlm.nih.gov/pubmed/37485307
http://dx.doi.org/10.2147/OTT.S272563