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Evaluation of Sinonasal Outcome Test (SNOT-22) Domains in the Assessment of the Quality of Life in Patients with Nasopharyngeal Carcinoma

BACKGROUND: Few instruments are available for assessing the otorhinologic-related quality of life (QOL) in nasopharyngeal carcinoma (NPC) patients. Therefore, we evaluated whether the 22-item Sinonasal Outcome Test (SNOT-22) could be applied to these patients. METHODS: Patients diagnosed with NPC, w...

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Autores principales: Wu, Ching-Nung, Wang, Yu-Ming, Chen, Wei-Chih, Fang, Fu-Min, Li, Shau-Hsuan, Huang, Tai-Lin, Hwang, Chung-Feng, Lee, Yu, Lin, Chung-Ying, Luo, Sheng-Dean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362877/
https://www.ncbi.nlm.nih.gov/pubmed/37485039
http://dx.doi.org/10.2147/CMAR.S416353
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author Wu, Ching-Nung
Wang, Yu-Ming
Chen, Wei-Chih
Fang, Fu-Min
Li, Shau-Hsuan
Huang, Tai-Lin
Hwang, Chung-Feng
Lee, Yu
Lin, Chung-Ying
Luo, Sheng-Dean
author_facet Wu, Ching-Nung
Wang, Yu-Ming
Chen, Wei-Chih
Fang, Fu-Min
Li, Shau-Hsuan
Huang, Tai-Lin
Hwang, Chung-Feng
Lee, Yu
Lin, Chung-Ying
Luo, Sheng-Dean
author_sort Wu, Ching-Nung
collection PubMed
description BACKGROUND: Few instruments are available for assessing the otorhinologic-related quality of life (QOL) in nasopharyngeal carcinoma (NPC) patients. Therefore, we evaluated whether the 22-item Sinonasal Outcome Test (SNOT-22) could be applied to these patients. METHODS: Patients diagnosed with NPC, who had been treated with standard protocol and followed up in our institute between 2019 and 2022, were invited to join the cross-sectional study during their clinic visits. All participants completed the SNOT-22 and Eustachian Tube Dysfunction Questionnaire-7 once they were recruited. Confirmatory factor analysis (CFA) was performed to decide the most suitable model for the underlying SNOT-22 subdomains, along with various validity and reliability tests. RESULTS: We identified a total of 275 patients, with 84 (30.5%) women and 191 (69.5%) men. The mean age was 54.1 years (standard deviation: 11.2). Among these patients, 171 (62.1%) were in late stages, and 260 (94.5%) received chemoradiotherapy as treatment. The median interval between primary RT treatment and questionnaire completion was 50 months (interquartile range: 29–93). CFA supported a five-factor model for the SNOT-22 for NPC patients, including nasal, ear/facial, sleep, function, and emotion domains. The internal consistency and test-retest reliability of the SNOT-22 domain score were good. In addition, known-group validity was good for the SNOT-22 total score and domain scores according to the disease recurrence status. CONCLUSION: Psychometric analyses supported the reliability and validity of a five-domain SNOT-22 for assessing otorhinologic-related QOL in NPC patients.
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spelling pubmed-103628772023-07-23 Evaluation of Sinonasal Outcome Test (SNOT-22) Domains in the Assessment of the Quality of Life in Patients with Nasopharyngeal Carcinoma Wu, Ching-Nung Wang, Yu-Ming Chen, Wei-Chih Fang, Fu-Min Li, Shau-Hsuan Huang, Tai-Lin Hwang, Chung-Feng Lee, Yu Lin, Chung-Ying Luo, Sheng-Dean Cancer Manag Res Original Research BACKGROUND: Few instruments are available for assessing the otorhinologic-related quality of life (QOL) in nasopharyngeal carcinoma (NPC) patients. Therefore, we evaluated whether the 22-item Sinonasal Outcome Test (SNOT-22) could be applied to these patients. METHODS: Patients diagnosed with NPC, who had been treated with standard protocol and followed up in our institute between 2019 and 2022, were invited to join the cross-sectional study during their clinic visits. All participants completed the SNOT-22 and Eustachian Tube Dysfunction Questionnaire-7 once they were recruited. Confirmatory factor analysis (CFA) was performed to decide the most suitable model for the underlying SNOT-22 subdomains, along with various validity and reliability tests. RESULTS: We identified a total of 275 patients, with 84 (30.5%) women and 191 (69.5%) men. The mean age was 54.1 years (standard deviation: 11.2). Among these patients, 171 (62.1%) were in late stages, and 260 (94.5%) received chemoradiotherapy as treatment. The median interval between primary RT treatment and questionnaire completion was 50 months (interquartile range: 29–93). CFA supported a five-factor model for the SNOT-22 for NPC patients, including nasal, ear/facial, sleep, function, and emotion domains. The internal consistency and test-retest reliability of the SNOT-22 domain score were good. In addition, known-group validity was good for the SNOT-22 total score and domain scores according to the disease recurrence status. CONCLUSION: Psychometric analyses supported the reliability and validity of a five-domain SNOT-22 for assessing otorhinologic-related QOL in NPC patients. Dove 2023-07-18 /pmc/articles/PMC10362877/ /pubmed/37485039 http://dx.doi.org/10.2147/CMAR.S416353 Text en © 2023 Wu et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Wu, Ching-Nung
Wang, Yu-Ming
Chen, Wei-Chih
Fang, Fu-Min
Li, Shau-Hsuan
Huang, Tai-Lin
Hwang, Chung-Feng
Lee, Yu
Lin, Chung-Ying
Luo, Sheng-Dean
Evaluation of Sinonasal Outcome Test (SNOT-22) Domains in the Assessment of the Quality of Life in Patients with Nasopharyngeal Carcinoma
title Evaluation of Sinonasal Outcome Test (SNOT-22) Domains in the Assessment of the Quality of Life in Patients with Nasopharyngeal Carcinoma
title_full Evaluation of Sinonasal Outcome Test (SNOT-22) Domains in the Assessment of the Quality of Life in Patients with Nasopharyngeal Carcinoma
title_fullStr Evaluation of Sinonasal Outcome Test (SNOT-22) Domains in the Assessment of the Quality of Life in Patients with Nasopharyngeal Carcinoma
title_full_unstemmed Evaluation of Sinonasal Outcome Test (SNOT-22) Domains in the Assessment of the Quality of Life in Patients with Nasopharyngeal Carcinoma
title_short Evaluation of Sinonasal Outcome Test (SNOT-22) Domains in the Assessment of the Quality of Life in Patients with Nasopharyngeal Carcinoma
title_sort evaluation of sinonasal outcome test (snot-22) domains in the assessment of the quality of life in patients with nasopharyngeal carcinoma
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362877/
https://www.ncbi.nlm.nih.gov/pubmed/37485039
http://dx.doi.org/10.2147/CMAR.S416353
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