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Neuroimmune characterization of optineurin insufficiency mouse model during ageing

Optineurin is a multifunctional polyubiquitin-binding protein implicated in inflammatory signalling. Optineurin mutations are associated with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), neurodegenerative diseases characterised by neuronal loss, neuroinflammation, and perip...

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Detalles Bibliográficos
Autores principales: Mohovic, Nikolina, Peradinovic, Josip, Markovinovic, Andrea, Cimbro, Raffaello, Minic, Zeljka, Dominovic, Marin, Jakovac, Hrvoje, Nimac, Jerneja, Rogelj, Boris, Munitic, Ivana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363168/
https://www.ncbi.nlm.nih.gov/pubmed/37481656
http://dx.doi.org/10.1038/s41598-023-38875-3