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Melanoma cells induce dedifferentiation and metabolic changes in adipocytes present in the tumor niche
BACKGROUND: One of the factors that affect the progression of melanoma is the tumor microenvironment, which consists of cellular elements, extracellular matrix, acidification, and a hypoxic state. Adipocytes are one of the types of cell present in the niche and are localized in the deepest layer of...
Autores principales: | Simiczyjew, Aleksandra, Wądzyńska, Justyna, Pietraszek-Gremplewicz, Katarzyna, Kot, Magdalena, Ziętek, Marcin, Matkowski, Rafał, Nowak, Dorota |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363323/ https://www.ncbi.nlm.nih.gov/pubmed/37481560 http://dx.doi.org/10.1186/s11658-023-00476-3 |
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